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How to Buy Spruce Biosciences (Spruce Biosciences) Stock

Buy Spruce Biosciences stock in 5 easy steps, view past price performance and learn what’s ahead for the company.

Spruce Biosciences is a biotechnology business based in the US. Spruce Biosciences shares (SPRB) are listed on the NASDAQ and all prices are listed in US Dollars. Spruce Biosciences employs 9 staff and has a trailing 12-month revenue of around $697,000.

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  4. Search for the stock name – SPRB. Search for the stock by name or ticker symbol.
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Spruce Biosciences stock price (NASDAQ: SPRB)

Use our graph to track the performance of SPRB stocks over time.

Spruce Biosciences shares at a glance

Information last updated 2025-12-01.
52-week range$4.28 - $240.00
50-day moving average $101.60
200-day moving average $611.67
Wall St. target price$209.50
PE ratio N/A
Dividend yield N/A
Earnings per share (TTM) $-84.32

Is it a good time to buy Spruce Biosciences stock?

The technical analysis gauge below displays real-time ratings for the timeframes you select. This is not a recommendation, however. It represents a technical analysis based on the most popular technical indicators: Moving Averages, Oscillators and Pivots. Finder might not concur and takes no responsibility.

This chart is not advice or a guarantee of success. Rather, it gauges the real-time recommendations of three popular technical indicators: moving averages, oscillators and pivots. Finder is not responsible for how your stock performs.

Spruce Biosciences financials

Revenue TTM $697,000
Gross profit TTM $-36,178,000
Return on assets TTM -76.92%
Return on equity TTM -167.93%
Profit margin 0%
Book value $9.56
Market Capitalization $107 million

TTM: trailing 12 months

Spruce Biosciences share dividends

We're not expecting Spruce Biosciences to pay a dividend over the next 12 months.

You may also wish to consider:

Have Spruce Biosciences's shares ever split?

Spruce Biosciences's shares were split on a 1:75 basis on 6 August 2025 . So if you had owned 75 shares the day before before the split, the next day you'd have owned 1 share. This wouldn't directly have changed the overall worth of your Spruce Biosciences shares – just the quantity. However, indirectly, the new 7400% higher share price could have impacted the market appetite for Spruce Biosciences shares which in turn could have impacted Spruce Biosciences's share price.

Spruce Biosciences share price volatility

Over the last 12 months, Spruce Biosciences's shares have ranged in value from as little as $4.275 up to $240. A popular way to gauge a stock's volatility is its "beta".

Beta is a measure of a share's volatility in relation to the market. The market (NASDAQ average) beta is 1, while Spruce Biosciences's is 3.493. This would suggest that Spruce Biosciences's shares are significantly more volatile than the average for this exchange and represent a higher risk.

To put Spruce Biosciences's beta into context you can compare it against those of similar companies.

Spruce Biosciences overview

Spruce Biosciences, Inc. is a biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders. The company develops TA-ERT, a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase, which is an enzyme replacement therapy for patients with Sanfilippo Syndrome Type B. It also develops Tildacerfont for treating a highly debilitating mental disorder characterized by depressed mood with cognitive-affective and somatic changes, including anhedonia, weight alterations, and altered sleeping patterns. In addition, the company develops SPR202 for the treatment of Congenital Adrenal Hyperplasia (CAH), a chronic and potentially life-threatening rare disease with no cure, and SPR204, a monoclonal antibody antagonist for Post-Bariatric Hypoglycemia. The company has a license agreement with Eli Lilly and Company to research, develop, and commercialize various pharmaceutical compounds. It also has a collaboration and license agreement with Kaken Pharmaceutical Co.

Frequently asked questions

What percentage of Spruce Biosciences is owned by insiders or institutions?
Currently 1.653% of Spruce Biosciences shares are held by insiders and 41.049% by institutions.
How many people work for Spruce Biosciences?
Latest data suggests 9 work at Spruce Biosciences.
When does the fiscal year end for Spruce Biosciences?
Spruce Biosciences's fiscal year ends in December.
Where is Spruce Biosciences based?
Spruce Biosciences's address is: 611 Gateway Boulevard, South San Francisco, CA, United States, 94080
What is Spruce Biosciences's ISIN number?
Spruce Biosciences's international securities identification number is: US85209E1091
What is Spruce Biosciences's CUSIP number?
Spruce Biosciences's Committee on Uniform Securities Identification Procedures number is: 85209E109

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