Finder makes money from featured partners, but editorial opinions are our own. Advertiser disclosure

How to Buy Spero Therapeutics Stock (SPRO)

Buy Spero Therapeutics stock in 5 easy steps, view past price performance and learn what’s ahead for the company.

Spero Therapeutics is a biotechnology business based in the US. Spero Therapeutics shares (SPRO) are listed on the NASDAQ and all prices are listed in US Dollars. Spero Therapeutics employs 32 staff and has a trailing 12-month revenue of around $40.5 million.

Our top picks for where to buy Spero Therapeutics stock

Top pick for stock bonuses

  • Trade stocks, options, ETFs, mutual funds, alternative asset funds
  • $0 commission on stocks, ETFs and options with no options contract fees
  • Get up to $1,000 in stock when you open and fund a new account within 45 days
  • Access to a financial planner
Probability of Member receiving $1,000 is a probability of 0.026%; If you don’t make a selection in 45 days, you’ll no longer qualify for the promo. Customer must fund their account with a minimum of $50.00 to qualify. Probability percentage is subject to decrease.

Terms and conditions apply*. For 401k rollovers, existing SoFi IRA members must complete 401k rollovers via this link For SoFi members without a SoFi IRA, a SoFi IRA must first be opened, and 401k rollover must be completed utilizing Capitalize via this link. SoFi and Capitalize will charge no additional fees to process a 401(k) rollover to a SoFi IRA. SoFi is not liable for any costs incurred from the existing 401k provider for rollover. Please check with your 401k provider for any fees or costs associated with the rollover. For IRA contributions, only deposits made via ACH and cash transfer from SoFi Bank accounts are eligible for the match. Click here for the 1% Match terms and conditions.

Up to 2% match

  • Trade stocks, ETFs, options, futures and bonds all in one place
  • $0 commissions on stocks, ETFs and equity options, with low contract fees
  • Deposit or transfer $10,000+ to earn a 2% Match Bonus. Plus: Get a $100 transfer fee reimbursement on your first brokerage transfer of $2,000 or more. T&C apply.

Top pick for simple, worldwide trading

  • Trade stocks, ETFs, mutual funds, options and cryptocurrency
  • Worldwide stock and options trading
  • Commission-free stocks, ETFs and no transaction fee mutual funds
  • Invest with as little as $1

How to buy Spero Therapeutics stock

  1. Choose a stock trading platform. Use our comparison table
  2. Open an account. Provide your personal information and sign up.
  3. Fund your account. Deposit funds into your account by linking your banking information or transfer funds from another trading account.
  4. Search for the stock name – SPRO. Search for the stock by name or ticker symbol.
  5. Buy the stock. Place your order. It's that simple.

Buy Spero Therapeutics stock from these online trading platforms

Compare special offers, low fees and a wide range of investment options among top trading platforms.
12 of 12 results
Finder Score Available asset types Stock trade fee Minimum deposit Cash sweep APY bullet point infobox
Finder score
Stocks, Options, ETFs, Cryptocurrency, Futures, Event contracts, High-yield cash account
$0
$0
3.50%
Get a free stock when you successfully sign up and link your bank account. T&Cs apply.
Trade stocks, options, crypto and more, with advanced trading tools, fractional shares and exclusive perks for Gold members.
Finder score
Stocks, Bonds, Options, Mutual funds, ETFs, CDs
$0.01
$250
2.83%
Leverage powerful trading tools and low margin rates to trade stocks, options, ETFs, mutual funds and bonds.
Finder score
Stocks, Bonds, Options, ETFs, Cryptocurrency, Investments, Retirement, Treasury Bills, High-yield cash account
$0
$0
3.6%
Get up to $10,000 and transfer fees covered when you move your portfolio to Public. T&Cs apply.
Build a diversified portfolio of stocks, bonds, options, ETFs and crypto, with a high-yield cash account and options contract rebates.
SoFi Wealth Management logo
Finder score
Finder score
Stocks, Options, Mutual funds, ETFs, Alternatives
$0
$0
0.01%
Get up to $1,000 in stock when you open and fund a new account. T&Cs apply.
Trade stocks, ETFs, and options with zero commissions, invest in IPOs or automate your portfolio, with exclusive perks available through SoFi Plus.
Webull logo
Finder score
Finder score
Stocks, Bonds, Options, ETFs, Futures, Money market funds
$0
$0
3.60%
Deposit or transfer $100,000+ to earn a 4% Match Bonus, or $2,000+ to earn a 3% Match Bonus. Plus: Get a $100 transfer fee reimbursement on your first brokerage transfer of $2,000 or more. T&Cs apply.
Trade stocks, ETFs and equity options commission-free, with access to futures, advanced charting tools, a robo-advisor and event trading powered by Kalshi.
Interactive Brokers logo
Finder score
Finder score
Stocks, Options, Mutual funds, ETFs, Cryptocurrency
$0
$0
3.83% Lite
4.83% Pro
Trade in a simulated trading environment and access a wide range of tradable assets.
eToro logo
Finder score
Finder score
Stocks, Options, ETFs, Cryptocurrency, Investments
$0
$0
3.75%
No commission stock, ETF and options trades, with 3.9% interest on your options account balance and no options contract fees. See full disclosure.
Acorns logo
Finder score
Finder score
Stocks, ETFs
$0
$0
N/A
Get a $20 bonus when you set up an account and make your first recurring investment (min. $5). T&Cs apply.
Automate investing with recurring contributions starting at $5 and invest spare change from everyday purchases.
Stash Investments LLC logo
Finder score
Finder score
Stocks, ETFs
$0
$0
0.1%
Get $5 when you sign up and deposit $5. T&Cs apply.
Bank, automate your portfolio or invest in individual stocks and ETFs for as low as $3 per month.
Wealthfront logo
Finder score
Finder score
Stocks, ETFs, High-yield cash account
$0
$500
3.75%
Get a $50 bonus when you sign up and fund a taxable automated investing account with at least $500. T&Cs apply.
Automate your stock and bond portfolio or trade individual stocks for as little as $1 apiece. Plus, earn 3.50% APY on your cash.
JPMorgan logo
Finder score
Finder score
Mutual funds, ETFs
$0
$25,000
N/A
Financial planning, advice and portfolio management. T&Cs apply.
Get ongoing access to an advisory team with personalized financial planning and expert-built portfolios. Provider terms & conditions apply
M1 Finance logo
Finder score
Finder score
Stocks, ETFs, Cryptocurrency
$0
$100
4.00%
Build a custom portfolio of stocks and ETFs with automatic rebalancing. Plus, earn 4.00% APY with a high-yield cash account.
loading
Showing 12 of 12 results

What is the Finder Score?

The Finder Score crunches 147 key metrics we collected directly from 18+ brokers and assessed each provider’s performance based on nine different categories, weighing each metric based on the expertise and insights of Finder’s investment experts. We then scored and ranked each provider to determine the best brokerage accounts.

We update our best picks as products change, disappear or emerge in the market. We also regularly review and revise our selections to ensure our best provider lists reflect the most competitive available.

Read the full Finder Score breakdown

Paid non-client promotion. Finder does not invest money with providers on this page. If a brand is a referral partner, we're paid when you click or tap through to, open an account with or provide your contact information to the provider. Partnerships are not a recommendation for you to invest with any one company. Learn more about how we make money.

Finder is not an advisor or brokerage service. Information on this page is for educational purposes only and not a recommendation to invest with any one company, trade specific stocks or fund specific investments. All editorial opinions are our own.

Spero Therapeutics stock price (NASDAQ: SPRO)

Use our graph to track the performance of SPRO stocks over time.

Spero Therapeutics shares at a glance

Information last updated 2025-12-01.
52-week range$0.51 - $3.22
50-day moving average $2.27
200-day moving average $1.77
Wall St. target price$4.00
PE ratio N/A
Dividend yield N/A
Earnings per share (TTM) $-0.79

Is it a good time to buy Spero Therapeutics stock?

The technical analysis gauge below displays real-time ratings for the timeframes you select. This is not a recommendation, however. It represents a technical analysis based on the most popular technical indicators: Moving Averages, Oscillators and Pivots. Finder might not concur and takes no responsibility.

This chart is not advice or a guarantee of success. Rather, it gauges the real-time recommendations of three popular technical indicators: moving averages, oscillators and pivots. Finder is not responsible for how your stock performs.

Spero Therapeutics price performance over time

Historical closes compared with the close of $2.4 from 2025-11-28

1 week (2025-11-26) 3.00%
1 month (2025-11-04) 2.13%
3 months (2025-09-04) 12.15%
6 months (2025-06-04) -9.77%
1 year (2024-12-04) 103.39%
2 years (2023-12-04) 95.12%
3 years (2022-12-02) 25.00%
5 years (2020-12-04) 17.45

Spero Therapeutics financials

Revenue TTM $40.5 million
Gross profit TTM $-21,162,000
Return on assets TTM -29.77%
Return on equity TTM -95.3%
Profit margin -108.11%
Book value $0.47
Market Capitalization $135.2 million

TTM: trailing 12 months

Spero Therapeutics share dividends

We're not expecting Spero Therapeutics to pay a dividend over the next 12 months.

Spero Therapeutics share price volatility

Over the last 12 months, Spero Therapeutics's shares have ranged in value from as little as $0.5052 up to $3.22. A popular way to gauge a stock's volatility is its "beta".

SPRO.US volatility(beta: 1.48)Avg. volatility(beta: 1.00)LowHigh

Beta is a measure of a share's volatility in relation to the market. The market (NASDAQ average) beta is 1, while Spero Therapeutics's is 1.479. This would suggest that Spero Therapeutics's shares are more volatile than the average for this exchange and represent, relatively-speaking, a higher risk (but potentially also market-beating returns).

Spero Therapeutics overview

Spero Therapeutics, Inc. , a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which is in Phase 3 development; and SPR720, a novel product candidate for first-line treatment of nontuberculous mycobacterial (NTM) pulmonary disease. It has license agreement with Meiji Seika Pharma Co. , Ltd. to support the development of tebipenem HBr; Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries; and Vertex Pharmaceuticals Incorporated for patents relating to the oral prodrug SPR720, as well as SPR719, an active metabolite. Spero Therapeutics, Inc.

Frequently asked questions

What percentage of Spero Therapeutics is owned by insiders or institutions?
Currently 24.332% of Spero Therapeutics shares are held by insiders and 16.083% by institutions.
How many people work for Spero Therapeutics?
Latest data suggests 32 work at Spero Therapeutics.
When does the fiscal year end for Spero Therapeutics?
Spero Therapeutics's fiscal year ends in December.
Where is Spero Therapeutics based?
Spero Therapeutics's address is: 675 Massachusetts Avenue, Cambridge, MA, United States, 02139
What is Spero Therapeutics's ISIN number?
Spero Therapeutics's international securities identification number is: US84833T1034
What is Spero Therapeutics's CUSIP number?
Spero Therapeutics's Committee on Uniform Securities Identification Procedures number is: 84833T103

Ask a question

Finder.com provides guides and information on a range of products and services. Because our content is not financial advice, we suggest talking with a professional before you make any decision.

By submitting your comment or question, you agree to our Privacy and Cookies Policy and finder.com Terms of Use.

Questions and responses on finder.com are not provided, paid for or otherwise endorsed by any bank or brand. These banks and brands are not responsible for ensuring that comments are answered or accurate.

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

More guides on Finder

Go to site